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Clark Gregg (Kinda/sorta) - Ultimate Spider-man
Well, to be fair, Clark provides the voice to the character and it is animated based on his role as "Agent Coulson" from SHIELD. This might be as close as you get to seeing him in tighty whities so take what you can get :-). Oh, and of course spider-man makes fun of him for being in "tighty whities" instead of boxers. ho-hum.